Prepare the slow cooker by coating it with a light coating of cooking spray.
Place the chicken breasts in the bottom of the slow cooker and season with salt, pepper, cumin, chili powder, and garlic powder and surround the chicken with the diced onion.
Add salsa,Great Northern beans, creamed corn, frozen corn, and chicken broth.
Cover and cook on Low for 6–7 hours or High for 3–4 hours, until the chicken is tender and fully cooked.
Remove the chicken, shred it with two forks, and return it to the slow cooker.
Stir in the shredded pepper jack cheese until melted and creamy.
Squeeze in the lime juice, stir again, and taste for seasoning before serving.